Biliary microhamartomas (von Meyenburg complexes), liver metastasis simulators: a series of eight cases




Javier A. Teco-Cortes, Departamento de Patología, Hospital General de México Eduardo Liceaga, Ciudad de México, México
Peter Grube-Pagola, Departamento de Anatomía Patológica, Instituto de Investigaciones Médico-Biológicas, Universidad Veracruzana, Veracruz, Ver., México
M. Esther Gutiérrez-Díaz Ceballos, Departamento de Patología, Hospital General de México Dr. Eduardo Liceaga, Ciudad de México, México
Gerardo B. Aristi-Urista, Departamento de Patología, Hospital General de México Dr. Eduardo Liceaga, Ciudad de México, México


Background: Von Meyenburg complexes are benign hamartomatous lesions, they are part of the spectrum of ductal plate malformations. They are rare, reported in 0.35-5.6% of the general population, predominantly in adults, with no clear predilection for sex. Objective: To present the clinical characteristics of Von Meyenburg complexes in our region. Method: We searched all cases with diagnosis of Von Meyenburg complexes in a period from 2012 to 2022, in our institutions. Results: We identified eight cases, with an average age of 59.25 years, with a predominance of females and with one case associated with gastric carcinoma. Conclusions: It is important to adequately recognize this entity, since due to its multifocal nature it can easily simulate metastasis, additionally, and its presence does not rule out other synchronous neoplasms.



Keywords: Hamartomas. von-Meyenburg. Bile ducts. Metastasis. Gastric carcinoma.