Pancreatic metastasis from undifferentiated pleomorphic sarcoma. An extremely rare entity




Ester Alonso-Batanero, Sección Hepatobiliopancreática, Servicio de Cirugía General y del Aparato Digestivo, Hospital Universitario Central de Asturias, Oviedo, España
Lorena Solar-García, Sección Hepatobiliopancreática, Servicio de Cirugía General y del Aparato Digestivo, Hospital Universitario Central de Asturias, Oviedo, España
Patricia Morales-del Burgo, Servicio de Anatomía Patológica. Hospital Universitario Central de Asturias, Oviedo, España
Alberto Miyar-de León, Sección Hepatobiliopancreática, Servicio de Cirugía General y del Aparato Digestivo, Hospital Universitario Central de Asturias, Oviedo, España


Undifferentiated pleomorphic sarcoma (UPS) is a very aggressive malignant tumor that originates in bone or soft tissues, being its most frequent location in the extremities. We present the case of a 71-year-old man who, two years of follow-up after a lower right limb UPS excision surgery, presented a single metastasis of sarcomatoid origin in the pancreas that was treated by cephalic pancreaticoduodenectomy. Sarcomatoid metastases to the pancreas are extremely rare. Resection of the metastasis is the only therapeutic alternative that has reported benefit in terms of the survival of these patients.



Keywords: Soft tissue sarcoma. Metastasis. Pancreatoduodenectomy. Pancreas.