Hikmet Pehlevan-Özel, Department of Surgery, Mamak State Hospital, Ankara, Turkey
Tolga Dinç, Department of General Surgery, School of Medicine, University of Health Sciences, Ankara City Hospital, Ankara, Turkey
Nermin D. Okay, Department of Surgery, General Surgery Clinic, Ankara City Hospital, Ankara, Turkey
Mesut Tez, Department of General Surgery, School of Medicine, University of Health Sciences, Ankara City Hospital, Ankara, Turkey
Objective: The systemic inflammation response index (SIRI) is a marker used to predict survival. The aim of this study is to examine the relationship between SIRI and clinicopathological features and survival. Method: The relationship between clinicopathological characteristics and survey and SIRI was retrospectively investigated. Results: A total of 178 patients were included in the study. Poor prognostic factors such as tumor size, t, T-stage, tumor-node-metastasis (TNM) stage, and CA19-9 level were found to have a statistically significant relationship with patients with high SIRI (p = 0.039, p = 0.001, p = 0.001 and p = 0.013, respectively). A high SIRI was found to be an independent and poor prognostic factor for 3-year and 5-year survival (p = 0.014 and p = 0.027, respectively). Conclusions: High SIRI was associated with a poor survival rate, as were advanced TNM stage, advanced T stage, larger tumor size, and elevated CA19-9 level; all these are poor prognostic markers for gastric cancer.
Keywords: Clinical features. Gastric adenocancer. Gastric adenocancer. Systemic inflammation response index.