Furkan B. Alptekin, Department of Psychiatry, Başakşehir Çam and Sakura Training and Research Hospital, Istanbul, Turkey
Sena Inal-Azizoğlu, Department of Psychiatry, Başakşehir Çam and Sakura Training and Research Hospital, Istanbul, Turkey
Aybegüm Uysal, Department of Psychiatry, Başakşehir Çam and Sakura Training and Research Hospital, Istanbul, Turkey
Hüseyin Ş. Burhan, Department of Psychiatry, Başakşehir Çam and Sakura Training and Research Hospital, Istanbul, Turkey
Oya Güçlü, Department of Psychiatry, Başakşehir Çam and Sakura Training and Research Hospital, Istanbul, Turkey
Objective: The objective of the study is to evaluate how electroconvulsive therapy (ECT) affects treatment-resistant depression, bipolar and schizophrenic patient groups, and suicide attempt histories and to evaluate the relationship between treatment variables and patient outcomes. Method: In a retrospective cohort study at the inpatient psychiatry clinic of Çam and Sakura City Hospital between January, 2021, and February, 2023, 103 patients receiving ECT were analyzed. They were categorized into two groups according to indications that suicide risk (n = 76) and resistance to pharmacotherapy (n = 27). Results: The analysis revealed no significant age (p = 0.374) or gender (p = 0.304) differences between groups. However, significant differences emerged in diagnostic distribution (p = 0.027), with the suicide risk group receiving more ECT sessions (13.6 ± 11.2, p = 0.025) and experiencing longer total seizure times (427 ± 325 s, p = 0.023) compared to the treatment-resistant group (8.5 ± 4.7 sessions and 279 ± 115 s, respectively). Conclusions: ECT’s therapeutic application does not differ from demographic variables but is influenced by clinical diagnosis, with suicide risk patients receiving more intensive treatment. These findings highlight the necessity of individualized ECT protocols and suggest that diagnostic considerations are critical in optimizing ECT treatment strategies. Despite its retrospective design, the study underscores the importance of personalized ECT regimens and calls for further prospective research to validate these findings.
Keywords: Electroconvulsive therapy. Suicide. Resistant to pharmacotherapy. Schizophrenia. Bipolar disorder. Depression.