The relationship between heart failure and smoking, and development of urethral stricture




Kutay Topal, Department of Urology, Afyonkarahisar State Hospital, Afyonkarahisar, Turkey
Arif Demirbas, Department of Urology, Bursa Doruk Hospital, Bursa, Turkey
Aydin Balci, Department of chest diseases, Afyonkarahisar Health Sciences, University, Afyonkarahisar, Turkey
Osman Gercek, Department of Urology, Afyonkarahisar Health Sciences University, Afyonkarahisar, Turkey
Kemal Ulusoy, Department of Urology, Afyonkarahisar Health Sciences University, Afyonkarahisar, Turkey
Mustafa Karalar, Department of Urology, Afyonkarahisar Health Sciences University, Afyonkarahisar, Turkey
Ibrahim Keles, Department of Urology, Afyonkarahisar Health Sciences University, Afyonkarahisar, Turkey


Objective: To evaluate the relationship between heart failure (HF), chronic obstructive pulmonary disease (COPD), and smoking with the development of urethral stricture (US) by examining the patients who underwent transurethral prostate resection procedure, with and without the development of US in their follow-ups. Methods: Among the patients who underwent transurethral resection of the prostate, 50 patients who developed US during their follow-ups formed group 1, while a total of 50 patients who did not develop US and were selected by lot formed group 2. The relationship between the patients’ data on HF, COPD and smoking status and the development of US was investigated. Results: The mean number of cigarettes smoked was statistically significantly high in the group with stricture (p = 0.007). Furthermore, pulmonary function test parameters of patients such as forced expiratory volume in 1 s (FEV1), forced vital capacity (FVC), and FEV1/FVC were found to be statistically significantly higher in Group 2 (p < 0.001, p < 0.001, and p = 0.008, respectively). In the logistic regression analysis, being a smoker was found to be the strongest predictor (p = 0.032). Conclusion: Our study concluded that smoking, HF, and COPD significantly increase the risk of developing stricture after transurethral resection of the prostate.



Keywords: Urethral stricture. Transurethral prostate resection. Smoking. Chronic obstructive pulmonary disease. Heart failure.