Survival rates and associated risk factors in colorectal cancer treatment

Objective: This study retrospectively investigates the risk factors affecting survival rates in patients with colorectal cancer. Methods: A total of 232 patients who underwent surgery between 2011 and 2016 were included in the analysis. The average age of the patients was 63.7 years, and the majority were male. Among these patients, 84.5% underwent elective surgeries, while 13.8% had liver metastases. Results: The findings revealed that survival is significantly influenced the type of surgery, tumor differentiation, the presence of liver metastases, carbohydrate antigen 19-9 (CA 19-9) levels, T and N stages, and the lymph node ratio. Patients who had poorly differentiated tumors, or exhibited elevated CA 19-9 levels demonstrated a higher risk of mortality. In addition, liver metastases were strongly regarding significantly lower survival rates. Conclusions: The study emphasized that survival rates decreased as the tumor stage progressed and patients who underwent elective surgery performed better. These findings emphasize the critical importance of early diagnosis and treatment planning. Identifying these risk factors is crucial for the development of personalised treatment strategies and further research with larger cohorts is essential to deepen and validate these associations.